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Successful Treatment of Chemical Burn with Self-retained Cryo-preserved Amniotic Membrane

Updated: Jul 25, 2020

To report an acute case of chemical burn successfully treated with cryo-preserved amniotic membrane (Prokera).

Importance of treating patient quickly and effectively with the latest technological advancements in medicine. With the use of the cryo-preserved amniotic membrane (Prokera), a patient has a chance to see again despite being splashed with acid to his right eye.


A male patient with extensive (90%) corneal and conjunctival epithelial defect secondary to acid burn in the right eye was referred to us after no improvement with conventional treatment for 5 days. Standard treatment included antibiotic drops, steroid, artificial tears with a bandage contact lens. Patient was then treatment with four self-retained cryo-preserved amniotic membranes (Prokera, which resulted in complete re-epithelialization of the cornea and conjunctiva in 31 days. Vision improved from 20/60 to 20/30. During 12 months of follow-up visits, the eye remained stable with clear cornea and no signs of perforation.

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